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CMC Use In The Pharmaceutical Industry

- Mar 18, 2015 -

CMC use in the pharmaceutical industry
In the pharmaceutical industry can be used for injection of emulsion stabilizer, tablet binders and film formers. It was proved by the foundation and the animal is safe CMC anticancer drug carrier. With CMC as membrane material developed by the transformation of traditional Chinese Yin Shengjisan formulations - - Yin Sheng sarcolemma, grinding can be used for skin wounds and traumatic surgical wounds. Animal model studies have shown that the membrane to prevent wound infection, no significant difference between the gauze dressings, wound tissue fluid exudation in control and rapid healing of the wound, this film is much better than gauze dressings, and reduce postoperative edema and wound stimulation. Polyvinyl alcohol: sodium carboxymethyl cellulose: carbopol Press 3: 6: 1 ratio of film former is made of optimum formulation, adhesion and release rate were increased, an increase in membrane mucoadhesive slow release adhesion agent, prolong the residence time and the efficacy of the formulation in the oral pharmaceutical formulation has significantly improved. Ding piperazine card as potent local anesthetic, but it can produce poisoning sometimes more serious cardiovascular side effects, it is widely used in clinical practice at the same time, bupivacaine, and prevention and treatment of its toxicity has been more attention. Pharmaceutical research shows, CIVIC as a slow-release material and bupivacaine solution preparation can significantly reduce the side effects of drugs. In PRK surgery, the use of low concentrations of tetracaine with non-steroidal anti-inflammatory drugs can significantly relieve joint pain after CMC. Prevention of peritoneal adhesions after abdominal surgery, to reduce the incidence of intestinal obstruction is one of the most concerned issue of Clinical Surgery. Studies have shown that, CMC reduce postoperative peritoneal adhesions was superior level of hyaluronic acid can be used as an effective way to prevent the occurrence of peritoneal adhesions. CMC for the treatment of liver cancer hepatic artery catheter anticancer drugs can prolong the anti-cancer drug in the tumor residence time, enhance the anti-tumor force, improve the therapeutic effect. In animal medicine, CMC also has a wide range of uses. It has been reported [2] that the ewes to within 1% CMC solution intraperitoneal infusion to prevent livestock childbirth, abdominal adhesions after surgery reproductive tract has a significant effect.

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